Stocks under development
Please Note:
The Type 1 Diabetes Resource does not hold all the stocks at The Jackson Laboratory relevant to type 1 diabetes research. Visit this link to see a compiled list of type 1 diabetes mouse models held by JAXMice.
Stocks Under Development
Below is a list of stocks which have been accepted for inclusion in the Type 1 Diabetes Resource, and are at varying stages of the importation process and our genetic quality control effort. When a stock is physically located in the T1DR colony, it is catalogued by primary genetic manipulation - please see Current stocks for these stocks.
If you are interested in any of these stocks, please contact the T1DR Project Manager. this interest will be catalogued and considered in shaping future wave distributions.
| Common name | Genetic manipulation | Stock no. | Formal strain nomenclature |
|---|---|---|---|
| NOD-Cr2 KO | 007789 | Approved | |
| NOD-Tg(IgM-Ctla4) | Transgenic | 007841 | Approved, not on campus NOD.FVB-Tg(Igh-6-Ctla4/Cd80)1Jbs/J |
| NOD.Catb | Knockout | 008051 | |
|
DR3b, NOD.Lc11b |
Allelic Congenic | 008055 | Approved - Not on campus, NOD.L-(D11Mit314-D11MitCsf2)/McdfJ |
| DR3g, NOD.Lc11g | Allelic Congenic | 008058 |
Approved - Not on campus, NOD.L-(D11Mit314-D11Mit339)(D11Mit364- D11Mit39)/ McdfJ |
| DR3i, NOD.Lc11i | Allelic Congenic | 008059 | |
| NOD.Zc4c | Allelic Congenic | 008065 | |
| NOD.Catl | Knockout | 008352 | |
| NOD.IGRP | transgenic | 008472 |
Approved - Not on campus, legal issues - not able to import NOD/ShiLt-Tg(H2-Ea-G6pc2)69Tkay/J |
| NOD.CatS | Knockout | 008524 | |
| Cd11b-DTR | transgenic | 008547 | |
| GFAP-B2m | transgeic, Knockout | 008542 |
Approved - Not on campus, NOD.129P2(B6)-B2m -/- Tg(GFAP-B2m)9Mdos/J |
| NOD.B10-Idd5 (R2 or 1092) | Congenic | 008893 | NOD.B10-Idd5C57Bl/6J/1092MrkJ |
| NOD.B10-Idd5 (974) | Congenic | 008894 | NOD.B10-Idd5C57Bl/6J/974MrkJ |
| 129-eNos KO | Knockout | 008286 | 129S6.Cg-Nos3tm1Unc/J |
| 129-Akita | Spontaneous Mutation | 007688 | 129S6.B6-Ins2Akita/CofJ |
| NOD.TCRa/b BDC12-4.1, Rag1 | Double transgenic, Knockout | The T1DR is developing this double transgenic, KO from stocks 006304, 006304 and 003729 | |
| NOD.Cd11c-YFP | Transgenic | 009422 | NOD.Cg-Tg(Itgax-EYFP)1Mnz/QtngJ |
| NOD-Yet40 | Targeted Mutation | 009618 |
Approved - Not on campus NOD.Cg-Il12b tm1Lky /JbsJ |