Targeted Mutation Stocks (Knockouts) - Live colony

Common Name Strain Designation Stock Number
NOD.CD28 KO NOD.129S2(B6)-Cd28tm1Mak/JbsJ

004761

NOD.Casp1 KO NOD.129S2(B6)-Casp1tm1Sesh/LtJ 004947
NOD.Ins2 KO NOD.129S2(B6)-Ins2tm1Jja/GseJ 005036
NOD.B2m, C2ta KO NOD.129(B6)-B2mtm1UncC2tatm1Ccum/BhsJ 005356
NOD-Ins2Tg1, Ins1KO, Ins2KO

NOD.Cg-Tg(Ins2*Y16A)1Ell Ins1tm1Jja Ins2tm1Jja/GseJ

 005524
NOD.DQ8, Ab0 NOD.Cg-Ab1tm1GruTg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/EllJ 006021
NOD.DQ8, Ab0, Rag1

NOD.Cg-Rag1tm1Mom H2-Ab1tm1Gru Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/EllJ

 006022
NOD.DQ6, Ab0 NOD.Cg-H2-Ab1tm1Gru Tg(CD4, HLA-DQA1, HLA-DQB1)N8Ell/EllJ 006023

NOD.DQ6, Ab0, Rag1

 NOD.Cg-Rag1tm1MomH2-Ab1tm1Gru Tg(CD4,HLA-DQA1, HLA-DQB1)N8Ell/EllJ 006024
NOD.Cd1d KO

NOD.129S2(B6)-Cd1d1/Cd1d2tm1Spb/SbwJ

 006330
NOD.ICAM1 KO (clean) NOD.129S4(B6)-Icam1tm1Jcgr/J 006351
NOD.Aire KO NOD.129S2(B6)-Airetm1.1Doi/DoiJ 006360
NOD.IgHEL, Igh -/- NOD.Cg-Igh-6tm1Cgn Tg(IghelMD4)4Ccg/DvsJ 006608
NOD.IL4 knockin NOD.Il4tm1Lky/JbsJ 006698

Targeted Mutation Stocks (Knockouts)- Cryopreserved

Targeted Mutations Available from Cryopreservation

Common Name

Strain Designation

Stock #

 NOD.B2m

NOD.129P2(B6)-B2mtm1Unc/J

 002309

 NOD.IFNnull NOD.129S7(B6)-Ifngtm1Ts/DvsJ

 002575

 NOD.Cd4null  NOD.129S6(B6)-Cd4tm1Knw/DvsJ

 003090

 NOD.Pfp

NOD.B6-Prftm1Sd/J

 003505

 NOD.IL4null

NOD.129P2(B6)-Il4tm1Cgn/DvsJ

 004222

NOD.CD38 NOD.129P2(B6)-Cd38tm1Lnd/LtJ

004311

NOD.IL-10null

NOD.Cg-Il10tm1Cgn/DvsJ

004266
NOD.IL4/10null

NOD.Cg-Il10tm1CgnIl4tm1Cgn/DvsJ

004291
 NOD.CD38  NOD.129P2(B6)-Cd38tm1Lnd /LtJ

004311

NOD.IF NRBnull

NOD.129S1(B6)-Ifngr2tm1Pbro/DvsJ

 004352
NOD.Tcratm1

NOD.129P2(C)-Tcratm1Mjo/DoiJ
 

 004444
NOD.CIITA
 

NOD.129S2(B6)-C2tatm1Ccum/FlvJ

 004448
NOD.Igh-6   NOD.129S2(B6)-Igh-6tm1Cgn/DoiJ 004639
 NOD.Stat4  NOD.129S2-Stat4tm1Gru/JbsJ

 004671

NOD.Stat6    NOD.129S2-Stat6tm1Gru/JbsJ 004672
NOD.B7-1/Rag1 NOD.129(B6)-Rag1tm1MonCd80tm1Shr/JbsJ

004673 

NOD.B7-2  NOD.129S4-Cd86tm1Shr/JbsJ

004762

 NOD.Itgb7, Sell  NOD.Cg-Selltm1TftItgb7tm1Cgn/LtJ  004943
 NOD.Igtb7  NOD.B6-Itgb7tm1Cgn /2Lt  004944
 NOD.Ins1  NOD.129S2(B6)-Ins1tm1Jja/GseJ

005035

 NOD.OX40L  NOD.129(B6)-Tnfsf4tm1Shr/DoiJ

005075

 NOD.IL1r1  NOD.Cg-Il1r1tm1Roml/HetJ

 005078

 NOD.Ica1  NOD.129-Ica1tm1Mdos/MdosJ

 005080

 NOD.Ctla4  NOD.129(B6)-Ctla4tm1All/DoiJ

 005144

 NOD.RAG1, CD80/86  NOD.Cg-Rag1tm1MomCd86tm2Shr/JbsJ

 005273

NOD.CD38, scid NOD.Cg-Cd38tm1LndPrkdcscid/LtJ

005345

NOD.IL10, Casp1

NOD.Cg-Il10tm1CgnCasp1tm1Sesh/LtJ

005346

 NOD.Cd8a  NOD.129S2(B6)-Cd8atm1Mak/DvsJ

005513

 BALB.Ncb5or  C.129S4-Cyb5r4tm1Hfb/HfbJ  005516
B6.Ncb5or  B6.129S4-Cyb5r4tm1Hfb/HfbJ

005517

NOD-Ins2 Tg3, Ins1KO, Ins2KO

NOD.Cg-Tg(Ins2*Y16A)3Ell Ins1tm1Jja Ins2tm1Jja/GseJ

005525

NOD.ICAM1

NOD.129S4(B6)-Icam1tm1Jcgr/SmtnJ

005983

Please Note: 

The Type 1 Diabetes Resource does not hold all the stocks at The Jackson Laboratory relevant to type 1 diabetes research. Visit this link to see a compiled list of type 1 diabetes mouse models held by JAXMice.