The Type 1 Diabetes resource
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at NIH is funding the Type 1 Diabetes Resource (T1DR) at The Jackson Laboratory. The purpose of this resource is to collect and cryopreserve 20-30 mouse stocks per year important to research in type 1 diabetes.
About the resource
The resource includes:
- NOD stocks carrying transgenes
- Targeted mutations (e.g. gene knockouts)
- NOD and NOD-related stocks congenic for chromosomal intervals containing T1D susceptibility or resistance loci
- Resources useful for the transplant of human stem cells and other tissues
The T1DR includes stocks donated by external investigators and stocks generated at The Jackson Laboratory . An advisory committee oversees the selection of stocks to be included in the T1DR.
An online form is available for investigators wishing to donate a stock. We are also soliciting suggestions for stocks that should be included in the T1DR.
Although the primary mission of the T1DR is cryopreservation of valuable mouse stocks, provisions are being made for each stock to be available for live distribution over a limited period of time. If you wish to be notified when various stocks are available for live distribution, please contact the project manager.
